http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/RSS.ashxiPaper PagesWed, 29 Feb 2012 05:02:07 +0100http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=1http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=1Continuing Education and Training for Laboratory Professionals 2012 Your Lab’s Best Friend! Webinars, TeleCOnferenCes and Online COurses www.laboratoryTraining.org APHL offers a range of high-quality continuing education and professional development programs to strengthen the skills of laboratorians and promote excellence in laboratory practice. Consult online listings for objectives, audience, description and continuing education contact hours. APHL designs courses for laboratory scientists working in clinical, public health, environmental, agricultural, veterinary and academic settings. Learning levels may be basic, intermediate or advanced.2012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=2http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=2Table of Contents Hot Topics .3 aPHl–Clsi series .4 infectious Diseases .6 Mass spectrometry . 10 Mycology. 11 Tuberculosis . 11 Molecular Methods . 12 Parasitology . 12 newborn screening. 12 Chromatography . 13 environmental. 16 sexually-Transmitted Disease . 16 Quality lab Practices . 17 Quality systems . 17 safety and Preparedness . 18 Quality Control . 18 asT. 19 Clia . 19 Yearly Training. 19 When registering, please provide the event Code found in parentheses after audience key. register Online Please visit www.LaboratoryTraining.org for more course information and easy registration. If you have difficulty with the online registration process, please email registrar@aphl.org or call 240.485.2727 from 8:00 AM to 4:30 PM ET. Continuing education The Association of Public Health Laboratories (APHL) is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.® Program. Participants who successfully complete an accredited program will be awarded contact hours accordingly, typically 1.0 contact hour for a webinar to 15.0+ contact hours for multiday workshop. P.A.C.E.® is accepted by all licensure states except Florida. Contact hours in the relevant category are awarded for Florida Laboratory Licensees. Consult online course description for full details. extra Value for Multiple Participants Many webinars and some online courses allow multiple participants for one registration fee. Consult registration instructions online. Webinar + Web archive recording Get extra training value by registering for webinars with six-month access to web archive recording after the webinar date. Want to attend, but have a schedule conflict? You can also register for any webinar you miss and access the web archive recording to earn continuing education credits. Don’t have access to an internet connection? You can still participant in the program over the phone as a teleconference. special needs In compliance with the Americans with Disabilities Act (ADA), individuals seeking special accommodations should notify the APHL Customer Service Manager by email (customersupport@aphl.org) at least three weeks prior to the program. auDienCe KeY P E C R A V Government public health labs Environmental labs Clinical and private labs Research labs Agricultural Labs Veterinary labs Association of Public Health Laboratories www.LaboratoryTraining.org 22012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=3http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=3HOT TOPICS Neisseria gonorrhoeae: Is Resistance a Concern in 2012? Although the incidence of N. gonorrhoeae has not increased in recent years, it continues to be a significant cause of sexually transmitted infections in the US and the world. In most laboratories, testing has been converted from culture to molecular methods, and consequently, susceptibility testing is not performed routinely. Through the efforts of the Gonococcal Infection Surveillance Program (GISP) and other groups, data is available about the present state of the art in regard to gonococcal antimicrobial resistance. Results of this data will be described in the context of the epidemiology of Neisseria gonorrhoeae today. Available until 7/17/2012 • $105 Archived Webinar CLSI 2012 AST Update Each January, CLSI updates standards for antimicrobial susceptibility testing (AST). It is important for clinical laboratories to incorporate the new recommendations into routine practice to optimize detection and reporting of antimicrobial resistance. In January 2012, the annual update of the M100 tables (CLSI document M100-S22) will be published along with updates of the standards that describe how to perform disk diffusion (M02-A11) and MIC tests (M07-A9). One of the highlights for 2012 will be revised interpretive criteria (breakpoints) for betalactams and Pseudomonas aeruginosa. These breakpoint changes and several other new recommendations found in M02-A11, M07-A9 and M100-S22 will be discussed. Available until 8/1/2012 • $95 APHL–CLSI Archived Webinar P C (588-900-12) P C V (588-601/602-12) Non-O157 Shiga Toxin-producing E. coli: It’s a New World Out There Despite incomplete knowledge of the distribution of non-O157 STEC and their role in disease, several recent outbreaks involving these agents illustrate their potential to cause widespread, serious disease. This presentation will review the evidence for the pathogenic significance of non-O157 STEC, discuss the CDC recommendations for clinical laboratories to include testing for all STEC in every routine stool culture, and describe testing protocols to demonstrate STEC. Available until 7/31/2012 • $105 Archived Webinar What a great teleconference! P C (588-902-12) www.LaboratoryTraining.org 32012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=4http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=4HOT TOPICS Cystic Fibrosis: Breathing More Easily? Molecular advances in cystic fibrosis research paints a picture of a much more complex disorder than previously thought. This program covers the latest diagnostic testing paradigms, clinical significance and future treatments envisioned for this condition. Available until 3/13/2012 Archived Webinar • $105 Standardization of Labels on Clinical Laboratory Specimens There is a high rate of mis-identified specimens in many clinical laboratories. Until recently, there was no standard to address the lack of standard format for specimen labels. Adoption of this standard by individuals who collect and handle specimens will contribute to a reduction in mislabeled specimens ensuring higher quality of reporting and faster delivery of results. Available until 3/29/2012 APHL–CLSI Archived Webinar • $195 P V (590-932-11) Use of Software to Perform Evaluation Protocols All clinical laboratories need to use evaluation protocols, which include Linearities, Precision, Trueness, Carryover, Drift, Comparability, Reference Interval, and Limit of Detection. Software has been created that incorporates these protocols and can address the difficult and timeconsuming task that laboratorians face when performing these evaluations. The use of software ensures automatic calculations and alignment with CLSI document guidelines. Demonstration of compliance with accreditation requirements for verification and validation of clinical laboratory assays is made easy with the use of this software. Available until 3/15/2012 APHL–CLSI Archived Webinar • $195 P C (590-630-11) Reference Intervals: Practical Approaches Arguably, one of the most important elements of a laboratory test is the reference interval, which comprises the values that help clinicians interpret their patients’ test results. This webinar will focus on ways laboratories can implement the most recent guidelines from CLSI document C28 to validate and establish reference intervals, with an emphasis on practical approaches applicable to virtually all laboratories. Available until 4/6/2012 APHL–CLSI Archived Webinar • $195 P C (590-629-11) P C (590-631-11) Receiver Operating Characteristic Curves for Assessing Accuracy Evidence-based medicine uses receiver operating characteristic (ROC) curves as a tool to determine diagnostic accuracy. One needs to know how the curves are created to properly interpret their use. This program describes how to create ROC curves, both in terms of subject selection and organization of the data. In addition, discussion focuses on ROC plot interpretation using quantitative and qualitative measures. Available until 5/17/2012 APHL–CLSI Archived Webinar • $195 CLSI–APHL Spring Series: April–June Six webinars >15% savings • $990 • (588-614-12) P C (590-634-11) www.LaboratoryTraining.org 42012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=5http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=5HOT TOPICS The Positive, the Negative, the Gram Stain: An Online Course This basic online ourse is for both new and seasoned laboratory profession¬als who routinely use this microbiology procedure. Using the Gram stain to characterize an organism is an initial step in routine bacterial identification. Direct specimen Gram stains provide rapid information regarding specimen quality, bacterial and cellular presence, and a presumptive diagnosis of infec¬tious agents. A thorough understanding of the Gram stain is foundational knowledge for anyone working in the microbiology laboratory. The course focuses on the uses, principles, procedures, interpretations and trouble¬shooting of this most universally performed microbiology stain. APHL and University of Nebraska Medical Center Online Course • $50 per person (588-705-11) ISO/IEC 17025 Quality Management Series These five high-quality pre-recorded webinars provide an introductory overview of the requirements for an accredited laboratory’s quality system using a comprehensive review of the management system requirements of ISO/IEC 17025:2005 and its documentation and record keeping requirements. Our instructors explain the management system clauses and provide examples to demonstrate how the standard can be applied. Participants will gain critical insight on the application of the requirements and the accreditation body’s perspective of meeting the requirements leading to accreditation. Available until 6/30/2013 Archived Webinar Series • $100 for series or $25 per webinar P E C R A V (588-720-12) auDienCe KeY P E C Government public health labs Environmental labs Clinical and private labs R A V Research labs Agricultural Labs Veterinary labs Establishing CLSI Breakpoints for Antimicrobial Susceptibility Testing A primary role of the CLSI (Standing) Subcommittee on Antimicrobial Susceptibility Testing is to set and revise breakpoints that are subsequently published in tables within CLSI document M100. The process for setting breakpoints is described in detail in CLSI document M23, and involves consideration of pharmacokineticpharmacodynamic (PK-PD) data, in addition to minimal inhibitory concentration distribution and clinical data. In this presentation, a brief primer about PK-PD principles will be provided. The role of PK-PD, as well as tools such as nonclinical infection models and Monte Carlo simulation to support decisions about CLSI breakpoints, will be reviewed. The PK-PD basis for recent breakpoint revisions listed in CLSI document M100-S21, such as those for carbapenems and Enterobacteriaceae, will be reviewed. This program is intended to help clinical microbiologists, clinicians and others involved with generating or using antimicrobial susceptibility test results better understand how PK-PD principles are used to establish breakpoints. Available until 6/8/2012 APHL–CLSI Archived Webinar • $195 I can’t wait for the webinar to start! P C (590-635-11) Association of Public Health Laboratories www.LaboratoryTraining.org 52012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=6http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=6INfECTIOUS DISEASES Pox Viruses and Public Health: Beyond Smallpox The poxvirus of the greatest historical significance is variola, the agent of smallpox and the single greatest killer of man of all infectious diseases known. Since the eradication program of the mid- to late-20th century resulted in the eradication of naturally occurring smallpox cases worldwide, the possible use of variola and other poxviruses as a bioweapon is a concern. Disease caused by monkeypox was recognized in primates as early as 1958 and has been the cause of ongoing human disease in central Africa since the 1980s. Monkeypox is of increased interest since its importation into the United States in 2003 and has increased concerns of zoonotic transmission of poxviruses. The emergence of human monkeypox highlights the importance of improving and maintaining diagnostic and clinical countermeasure capacities not only for variola, but also other poxviruses. Available until 7/24/2012 • $105 Archived Webinar Culture and Identification of Anaerobes: An Update Are you still mystified by anaerobes? This lecture will summarize the currently available methods for culturing and identifying clinically important anaerobic bacteria, including selection of appropriate specimens, use of selective media, special potency disks, identification disks and genotypic identification methods. Available until 8/21/2012 • $105 Archived Webinar P C (588-905-12) Emerging and Resurging Infectious Diseases: 2012 Join us for our annual infectious disease update. This program will provide an overview of recent outbreaks of infectious diseases attributed to emerging and resurging infectious diseases. For each disease discussed, lessons for and responsibilities of the Sentinel Microbiology Laboratory will be highlighted. 4/24/2012 • $105 Webinar plus six-month Web archive access P C V (588-901-12) Non-O157 Shiga Toxin-producing E. coli: It’s a New World Out There Despite incomplete knowledge of the distribution of non-O157 STEC and their role in disease, several recent outbreaks involving these agents illustrate their potential to cause widespread, serious disease. This presentation will review the evidence for the pathogenic significance of non-O157 STEC, discuss the CDC recommendations for clinical laboratories to include testing for all STEC in every routine stool culture, and describe testing protocols to demonstrate STEC. Available until 7/31/2012• $105 Archived Webinar P C (588-914-12) Laboratory Diagnosis of Lyme Disease in North America National surveillance data show that the number of reported Lyme disease cases has increased steadily over the last 20 years, with more than 30,000 cases in 2010. As case numbers and areas of risk have increased, so has the need to standardize and improve laboratory confirmation of infection. This program will review laboratory aspects of Lyme disease in the US, current guidelines for sero-diagnosis and methodologies and practices that could potentially improve future diagnosis and case management. 5/17/2012 • $105 Webinar plus six-month Web archive access P C (588-902-12) P C V (588-917-12) www.LaboratoryTraining.org 62012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=7http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=7INfECTIOUS DISEASES Anaerobic Bacteria Susceptibility Testing Antimicrobial resistance patterns for many anaerobic bacteria have changed significantly over the last several years. The general indications and rationale for testing organisms and choosing agents to test will be discussed. Also, the two CLSI-approved reference methods for determining MIC endpoints for anaerobic organisms will be described, along with more detailed discussion about endpoint determination. We will focus on material presented in the recently released CLSI M11 document addressing methods for antimicrobial susceptibility testing of anaerobic bacteria. 06/21/12 • $195 APHL–CLSI Webinar plus six-month Web archive access Tentative: Campylobacter Update HIV Diagnostics: New Tests and New Algorithms This presentation describes new HIV diagnostics that have received FDA approval and diagnostic algorithms that take advantage of the unique characteristics of these tests. Available until 4/15/12 Archived Webinar • $90 Funded in part by an unrestricted education grant from Abbott Diagnostics. P P C V (588-612-12) C (590-920-11) 2012 Influenza Update Flu seasons are unpredictable in a number of ways. What will happen in the 2012–2013 influenza season? This program will provide an overview of influenza and available diagnostic methods. The significance of influenza as a public health issue, expectations for the upcoming season, and the status of novel influenza strains in the world will also be described. 9/25/2012 • $105 Webinar plus six-month Web archive access auDienCe KeY P E C Government public health labs Environmental labs Clinical and private labs R A V Research labs Agricultural Labs Veterinary labs P C (588-924-12) Safety first! www.LaboratoryTraining.org 72012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=8http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=8INfECTIOUS DISEASES Multidrug-Resistant Gram Negative Rods (MDR-GNR) Series Register for an individual program or save on the series. Series price: $255 New Laboratory Guidelines for Syphilis In the last decade there have been major changes and improvements in STD testing technologies. While these changes have created great opportunities for more rapid and accurate STD diagnosis, they may also create confusion when laboratories attempt to incorporate new technologies into the existing structure of their laboratory. In this presentation, Dr. Steece presents an overview of syphilis screening technologies. He focuses on the new CDC Laboratory Guidelines for Syphilis and the possible impact this may have on laboratories. Available until 3/8/12 Archived Webinar • $105 P C (588-935-12) AST of GNR to Accurately Detect/Report MDR Isolates The first step to control spread of MDR-GNR is to identify patients that harbor these bacteria; accurate AST and effective reporting protocols are essential. This session will discuss the latest recommendations for reliable detection and reporting of MDR-GNR to include strategies for testing less conventional antimicrobial agents, when indicated. 10/2/2012 • $105 Webinar plus six-month Web archive access P C (590-918-11) Should We Be Concerned About Trichomonas vaginalis? According to the Centers for Disease Control and Prevention (CDC), trichomoniasis is the most common curable sexually transmitted infection (STI) in young, sexually active women. It is estimated that North America has between 5 and 8 million new infections each year, with an estimated rate of asymptomatic cases as high as 50%. This presentation addresses the epidemiology of the disease, including the unique patient population affected and sequelae for this STI. A comparison of testing options including the new rapid antigen testing and transcription-mediated amplification methods and a plan for implementation of these tests are also discussed. Available until 3/27/12 Archived Webinar • $105 P C (588-923-12) Confronting the Dilemma of MDR-GNR in Healthcare Facilities Control of MDR-GNR requires efforts of many disciplines in the healthcare system. Infection control, pharmacy, microbiology and infectious diseases all play a role. This session will look at ways these areas can work individually and together to protect patients and others from MDRGNR. 10/9/2012 $105 Webinar plus six-month Web archive access P C (588-925-12) P C (590-908-11) Treatment Strategies for Infections Due to MDR-GNR MDR-GNR can cause a variety of different types of infections and management of them can be challenging. Optimal therapy regimens have not been identified for certain infections caused by isolates resistant to all or most available antimicrobial agents. The latest developments for managing infections due to MDR-GNR will be presented during this session. 10/16/2012 • $105 APHL–CLSI Webinar plus six-month Web archive access 2011 Influenza Update As a result of Novel H1N1, influenza was pandemic in the United States and around the world last year. What will happen in the 2011–2012 influenza season? This program provides an overview of influenza and available diagnostic methods. The significance of influenza as a public health issue, expectations for the upcoming season and the status of novel influenza strains in the world are also described. Available until 4/1/12 Archived Webinar • $105 P C (588-926-12) P C (590-901-11) www.LaboratoryTraining.org Association of Public Health Laboratories 82012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=9http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=9INfECTIOUS DISEASES RESPIRATORY BACTERIAL PATHOGENS Although community-acquired pneumonia is often treated empirically, a significant number of respiratory cultures submitted to the routine bacteriology laboratory are from patients with symptoms of this infection. It is important for laboratories to be able to distinguish bacterial pathogens from normal flora in respiratory specimens, identify these pathogens and perform antimicrobial susceptibility tests when indicated. These sessions focus on strategies for identification of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and other bacterial pathogens encountered in respiratory specimens and reporting results effectively. Antimicrobial susceptibility testing of these organisms when isolated from respiratory specimens are discussed from a “When and How“ perspective. A clinician explains the use of laboratory reports to manage patients with community-acquired pneumonia. Respiratory Bacterial Pathogens: Identification and Reporting Available until 3/11/12 Archived Webinar • $105 P C (590-904-11) Respiratory Bacterial Pathogens: Clinical Relevance Available until 3/15/12 Archived Webinar • $105 P C (590-906-11) Respiratory Bacterial Pathogens: Susceptibility Testing Available until 3/18/12 Archived Webinar • $105 P C (590-905-11) auDienCe KeY P E C Government public health labs Environmental labs Clinical and private labs R A V Research labs Agricultural Labs Veterinary labs How long did you incubate these plates? www.LaboratoryTraining.org 92012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=10http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=10MASS SPECTROMETRY INDUCTIVELY-COUPLED PLASMA MASS SPECTROMETRY (ICP-MS) SERIES Online Course Series • Supported in part by PerkinElmer• $149 Series Inductively-Coupled Plasma Mass Spectrometry (ICP-MS) Applications This program covers both clinical and environmental applications of Induc¬tively-Coupled Plasma Mass Spectrometry (ICP-MS). The section on clinical applications covers an introduction of the ICP-MS with reference to typical clinical analysis, sample preparation, interferences with clinical samples, any needed maintenance in running samples and quality control. The section on environmental applications covers the use of ICP-MS for environmental samples, primarily drinking waters. Also included is an overview of the EPA methodologies and sample preparation as well as quality control. PerkinElmer and APHL Online Course • $75 E C R V P (588-701-11) Inductively-Coupled Plasma Mass Spectrometry (ICP-MS) Overview and Theory This program includes an introduction to the concepts and hardware used in inductively-coupled plasma mass spectrometry (ICP-MS). Topics of discus¬sion include applications and sample ranges that may be analyzed on this instrument. Other topics of discussion include the samples introduction area, interface and quadrupole principles and detector basics. An overview of inter¬ferences and how to correct for these interferences is discussed. PerkinElmer and APHL Online Course • $75 E C R V P (588-704-11) E C R V P (588-702-11) Inductively-Coupled Plasma Mass Spectrometry (ICP-MS) Basic Operation and Running Analysis This program covers the typical items operators may perform as part of the operation of ICP-MS instrumentation. Included will be items such as hardware set up and utilizing the software to perform daily checks and per¬formance. This program also includes guidelines to running analysis and the proper way of shutting down the unit. PerkinElmer and APHL Online Course • $75 Any Crypto in there? E C R V P (588-703-11) auDienCe KeY P E C Government public health labs Environmental labs Clinical and private labs R A V Research labs Agricultural Labs Veterinary labs Association of Public Health Laboratories www.LaboratoryTraining.org 102012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=11http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=11MYCOLOGY SERIES Register for an individual program or save on the series. Series price: $340 TUBERCULOSIS SERIES Join us for this three-part series on tuberculosis testing. Quality laboratory testing is essential in order to reach the goal of TB elimination in the US. Improvements in laboratory testing must be maintained and translated into expedited and improved treatment and control. It is imperative that the laboratory community provides healthcare providers and TB controllers with accurate smear, culture, drug susceptibility and molecular results within acceptable turn-around times. Register for an individual program or save on the series. Series price: $255 P C V (588-934-12) Differentiating Between the Dimorphic fungi and Their Doppelgangers Is that really a dimorphic fungi or is it a doppelganger? This program will focus on the dimorphic fungi regarding the disease process and differentiating them from species that mimic them by microscopic morphology. 5/8/2012 • $105 Webinar plus six-month Web archive access P C (588-936-12) P C V (588-916-12) TB 101 11/8/2012 • $105 Webinar plus six-month Web archive access Updates for Antifungal Susceptibility Testing This lecture will discuss antifungal susceptibility testing with newly described categorical breakpoints for several Candida spp. In addition, commercially available systems will be compared and contrasted in an effort to help laboratories determine methods that may best fit their clinical setting. 6/5/2012 • $105 Webinar plus six-month Web archive access P C (588-921-12) NAAT, IGRA and Genotyping: Using Nontraditional TB Tests Well 11/13/2012 • $105 Webinar plus six-month Web archive access P C V (588-919-12) P * Supported by a generous educational grant from QIAGEN C (588-922-12) CNS Mould Infections: Etiologic Agents and Their Identification This program will discuss filamentous etiologic agents of central nervous system (CNS) disease and provide guidelines for identification of selected fungi. 10/23/2012 • $105 Webinar plus six-month Web archive access Susceptibility Testing of M. tuberculosis: An Update 11/27/2012 • $105 Webinar plus six-month Web archive access P C (588-930-12) P C V (588-928-12) Selected Uncommon Hyaline Moulds: Their Significance and Identification What’s new in mycology? During this lecture, we will discuss the current taxonomy, significance and identification of selected, uncommon, hyaline filamentous fungi. 10/30/2012 • $105 Webinar plus six-month Web archive access P C V (588-929-12) www.LaboratoryTraining.org Association of Public Health Laboratories 112012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=12http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=12MOLECULAR METHODS Validation/Verification of Infectious Disease Molecular Tests There is a lot of confusion about the terms validation and verification and what studies need to be done before implementing an FDA-approved/cleared or laboratorydeveloped molecular test in a clinical laboratory. This webinar will review the requirements as defined by CLIA and describe methods for carrying out and evaluating the required studies. Available until 8/28/2012 • $105 Archived Webinar PARASITOLOGY Cryptosporidium: A Common Waterborne Parasite Cryptosporidium is a common waterborne intestinal parasite that is easily spread from person-to-person, and presents challenges to water purification. This program will cover the basic biology of the parasite, human infections and the laboratory tests used for diagnosis. Challenges presented by this single-celled parasite will be illustrated through a discussion of outbreaks. 4/3/2012 • $105 Webinar plus six-month Web archive access P C R A V (588-906-12) P E C A V (588-911-12) The Beginner’s Guide to Establishing Molecular Diagnostic Testing The use of molecular tests is expected to increase in medical settings in which technical knowledge may be limited. To bridge this gap, CLSI document MM19, Establishing Molecular Testing in Clinical Laboratory Environments; Approved Guideline, provides guidance for strategic planning, facility design, implementation and quality management for introduction of molecular diagnostic clinical programs. 3/1/2012 • $195 APHL-CLSI Webinar plus six-month Web archive access Separated at Birth: Differentiating Parasitic Lookalikes Some parasitic organisms were “separated at birth”: they resemble each other so strongly under the microscope that it is easy to confuse them. In many cases, these lookalikes have very different clinical implications, which means it’s especially important to be able to distinguish between them. In this presentation, we will describe lookalike pairs and give tips for their accurate diagnosis. 4/17/2012 • $105 Webinar plus six-month Web archive access P C V (588-913-12) P E C R A V (588-604-12) NEWBORN SCREENING New Guidelines for Cystic Fibrosis Newborn Screening Laboratory Tests This presentation will review three main topics: guidelines specific to the biochemical and molecular laboratory tests using the dried blood spot matrix, including quality control and quality assurance; important considerations when establishing a mutation panel; and the strengths and limitations of the various approaches for primary and second-tier testing. Intermediate Level Available until 7/26/2012 • $195 APHL–CLSI Archived Webinar auDienCe KeY P E C Government public health labs Environmental labs Clinical and private labs R A V Research labs Agricultural Labs Veterinary labs P C (588-611-12) www.LaboratoryTraining.org 122012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=13http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=13CHROMATOGRAPHY Chromatography Series These educational programs help managers, supervisors, laboratorians and analysts improve the quality and efficiency of the laboratory. The series consists of four seminars on liquid and gas chromatography, addressing fundamentals of separation and progressing from theory to practical applications. Each recorded seminar is divided into hour-long webinar programs. Beginning and advanced chromatographers both will benefit from these in-depth, dynamic sessions. Participants completing all 4 seminars will be awarded 23 contact hours of continuing education credit. APHL and Restek Webinar Series Supported in Part by Restek Corporation Register for all four webcast seminars for $449, individual seminars for $149. Includes all of the following modules for 5 contact hours of CE credit: • Introduction to GC • Column Selection • Sample Introduction • Detector Systems • Maintenance and Troubleshooting APHL and Restek Webinar • $149 (588-682-11) Seminar 3: LC/MS Chromatography At the conclusion of this seminar, the participant will be able to: • Discuss the selection and optimization of LC/MS systems in a wide variety of applications; • Outline LC/MS interfaces and method development, including quantitative LC/MS; and • Summarize practical applications, maintenance and troubleshooting for general use and specific analyses including THC metabolites, wastewater testing and newborn screening by tandem LC/MS. Includes all of the following modules for 6 contact hours of CE credit: • Introduction to LC/MS • LC/MS Analyzers • LC/MS Interfaces • LC/MS Method Development • Practical Applications: Case Studies • Maintenance and Troubleshooting P E C R V (588-685-11) Seminar 1: Liquid Chromatography At the conclusion of this seminar, the participant will be able to: • Outline fundamentals, best practices and latest developments in high pressure liquid chromatography (HPLC); • Describe how separations work and how to select the correct column and mobile phase and how to optimize a detection system; and • Conduct routine maintenance and troubleshooting of instrument and procedure. Includes all of the following modules for 6 contact hours of CE credit: • Introduction to HPLC • Modern HPLC Systems • Separation Techniques • Column Selection • Method Development • Maintenance and Troubleshooting APHL and Restek Webinar • $149 (588-683-11) Seminar 4: GC/MS Chromatography At the conclusion of this seminar, the participant will be able to: • Outline the advantages of coupling GC and MS; • Describe common ionization techniques and most common analyzers; • Summarize the importance of injection techniques, column selection and basic spectral interpretation in maintaining data quality and accuracy; and • Review effective maintenance and troubleshooting techniques. Includes all of the following modules for 6 contact hours of CE credit: • Introduction to GC/MS • Mass Spectrometric Detectors • Inlets and Injection Techniques • Column Selection • Basic Spectral Interpretation • Maintenance and Troubleshooting APHL and Restek Webinar • $149 (588-681-11) Seminar 2: Gas Chromatography At the conclusion of this seminar, the participant will be able to: • Review the factors affecting separations, GC components and sample introduction techniques; • Discuss injector maintenance for reducing system contamination; • Contrast the fundamental differences among detectors and how they affect quantitative analysis and suitability for particular applications; and • Describe correct column installation and best practices for maintenance and troubleshooting. APHL and Restek Webinar • $149 (588-684-11) www.LaboratoryTraining.org 132012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=14http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=14CHROMATOGRAPHY Liquid Chromatography (LC) Method Development Webcast Series APHL and Restek Webinar Series • $149 Supported in Part by Restek Corporation Restek Corporation and the Association of Public Health Laboratories (APHL) have embarked on a joint venture to present educational programs to clinical and public health laboratories. Programs are based on current Restek seminars and will help managers, supervisors, and analysts improve the quality and efficiency of their laboratories. This course provides the knowledge and tools necessary for the chromatographer to understand why a particular stationary phase would be chosen for separating various analytes and how to improve selectivity by choosing the proper eluent. Both beginning and advanced chromatographers will benefit from these dynamic, in-depth sessions. Module 1: Introduction to Systems and Chromatography Principles A practical review of modern liquid chromatography systems, including operation, and the fundamental principles and terminology will be presented. This section includes definitions, operational considerations and quality measures associated with this important technique. Module 4: Practical Method Development Part I A key challenge facing every laboratory analyst is proper method development. In Part I, a step-by-step process will be presented for fast and effective method development, which includes running scouting gradients. Module 5: Practical Method Development Part II Part II will develop a more in-depth process of developing a method, focusing on operational adjustments like mobile phase compositions, temperature, etc. We will also discuss the validation criteria needed for assessing effective analytical methods. Module 2: Understanding Separation Theory A detailed explanation of the theoretical plate model of chromatography will be presented. This will be used to define the operational parameters needed for system optimization and proper column choices. Module 3: Selecting a Separation Modes of separation are presented and discussed in detail, emphasizing stationary phase choices and how they participate in separation mechanisms. Objectives At the conclusion of this program, the participant will be able to: • Outline fundamentals and best practices in high pressure liquid chromatography (HPLC) and system performance. • Explain how separations work, separation theory and the parameters associated with liquid separations. • State a useful guideline for developing a step-by-step process of method development. • Describe the characteristics of method validation to assess an effective analytical method. P E C R V (588-616-11) Association of Public Health Laboratories www.LaboratoryTraining.org 142012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=15http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=15CHROMATOGRAPHY Gas Chromatography (GC) Head Space Seminar Webcast Series Available until 6/14/2012 APHL and Restek Webinar Series • $149 Supported in Part by Restek Corporation Restek Corporation and the Association of Public Health Laboratories (APHL) have embarked on a joint venture to present educational programs to clinical and public health laboratories. Programs are based on current Restek seminars and will help managers, supervisors and analysts improve the quality and efficiency of their laboratories. Each of the modules are recorded and available for review or training of new staff. Both beginning and advanced chromatographers will benefit from these dynamic, in-depth sessions. Module 1: Introduction and Chemistry of Headspace Analyse A solid review of headspace processes, terminology and operations. Includes a discussion on headspace theory, definitions, operational considerations and quality measures associated with this important technique. Module 4: Method Development Knowing how to approach method development efficiently can save time and reduce headaches. Gain critical skills and insight from experienced chemists. Follow along as we walk you through the process of identifying analytical and separation goals, select preliminary conditions, optimize parameters and validate your final method. Module 2: Sample Preparation and Handling Understanding the steps required to prepare a suitable headspace sample prior to analysis is vital for obtaining optimal headspace results. Sample vial geometry, types of vial and seal hardware and sample preparation technique can all affect peak response. Optimization of the vial/sample system and other unique sample preparation techniques will be considered. Module 5: Maintenance and Troubleshooting Performing routine maintenance on your GC and Headspace instruments is crucial for obtaining the best chromatographic results. Learn the keys to keeping your instruments operating at peak performance. Develop your own approach to solving instrument performance problems as we work through several troubleshooting exercises. Module 3: GC Principles and Modes of Operation This unit provides a comprehensive examination of sample introduction techniques, autosampler interfaces for GC, and GC instrument set up. Critical factors that affect chromatographic separations including capillary column chemistry as well as GC detector theory and operation will also be considered. Objectives At the conclusion of this program, the participant will be able to: • Discuss headspace theory and practice, selecting proper sampling techniques and optimize headspace methods asapplied to a wide variety of clinical and environmental samples. • Outline the steps necessary for proper headspace method development. • Summarize the principles and modes of operation of gas chromatographic systems when performing headspace analysis. P E C R V (588-622-11) Association of Public Health Laboratories www.LaboratoryTraining.org 152012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=16http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=16ENVIRONMENTAL Environmental Laboratory Ethics and Data Integrity: An Auditor’s Perspective Need annual environmental ethics training? This year we will be looking at ethics training through an auditor’s perspective. The program will focus on what an auditor looks for when evaluating data integrity and proper ethical conduct, tools that an auditor uses to uncover problems and how lab management can “think like an auditor” to evaluate their laboratory’s practices and procedures. 3/20/2012 • $105 Webinar plus six-month Web archive access SExUALLY-TRANSMITTED DISEASE Neisseria gonorrhoeae: Is Resistance a Concern in 2012? Although the incidence of N. gonorrhoeae has not increased in recent years, it continues to be a significant cause of sexually transmitted infections in the US and the world. In most laboratories, testing has been converted from culture to molecular methods, and consequently, susceptibility testing is not performed routinely. Through the efforts of the Gonococcal Infection Surveillance Program (GISP) and other groups, data is available about the present state of the art in regard to gonococcal antimicrobial resistance. Results of this data will be described in the context of the epidemiology of Neisseria gonorrhoeae today. Available until 7/17/2012 • $105 Archived Webinar E (588-909-12) Environmental Laboratory: Traceability Series The series is divided into three one-hour sessions to present the requirements for traceability for standards, reagents, samples, data, equipment, software and methods used in the laboratory. This series will review techniques for traceability and the elements needed for documentation as required by the TNI standard and recommended to provide efficient laboratory operation. Register for an individual program or save on the series Series Price $255 P C (588-900-12) Treponemal-Based Immunoassay for Primary Syphilis Screening Historically, many clinical laboratories have used the RPR assay for primary syphilis screening. Newer immunoassays that are treponemal-based are being used to replace the RPR and are becoming the primary screening test for syphilis in some clinical laboratories. The CDC has also addressed the implementation of these immunoassays in clinical laboratories and has recommended algorithms. This session will discuss the experience of implementing a treponenal-based immunoassay for primary syphilis screening in a large clinical microbiology laboratory and discuss CDC recommendations surrounding these assays. This program is supported in part by an unrestricted education grant from Trinity Biotech. 6/12/2012 • $105 Webinar plus six-month Web archive access E (588-933-12) Environmental Traceability: Standards and Reagents 3/6/2012 • $105 Webinar plus six-month Web archive access E (588-907-12) Environmental Traceability: Samples and Data 4/12/2012 • $105 Webinar plus six-month Web archive access P C (588-908-12) E (588-918-12) Environmental Traceability: Equipment, Software and Methods 5/29/2012 • $105 Webinar plus six-month Web archive access auDienCe KeY P E C Government public health labs Environmental labs Clinical and private labs R A V Research labs Agricultural Labs Veterinary labs E (588-920-12) Association of Public Health Laboratories www.LaboratoryTraining.org 162012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=17http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=17QUALITY LAB PRACTICES An Overview of the Bloodborne Pathogen Standard OSHA’s Bloodborne Pathogens Standard was instituted to protect healthcare workers against the health hazards from exposure to blood and other potentially infectious materials, and to reduce their risk from this exposure. This program presents an overview of the OSHA Bloodborne Pathogen Standard 1910.1030. Requirements of the standard with an emphasis on the exposure control plan, engineering and work practice controls, personal protective equipment (PPE), regulated waste, medical training and record requirements are discussed. Available until 5/1/12 Archived Webinar • $105 QUALITY SYSTEMS Basics of Provider-Performed Microscopy Provider-performed microscopy (PPM) procedures require the use of microscopic observation with minimum specimen preparation, typically performed by a provider in near-patient testing environments. This category of testing exists due to the nontransferable nature and labile nature of the specimens addressed in testing processes. Those performing PPM procedures include physicians and nonphysician providers. Basic Level 4/19/2012 • $195 APHL–CLSI Webinar plus six-month Web archive access P C (588-607-12) P C (590-915-11) Using Receiver Operating Characteristic Curves for Assessing Accuracy Evidence-based medicine uses receiver operating characteristic (ROC) curves as a tool to determine diagnostic accuracy. One needs to know how the curves are created to properly interpret their use. This program describes how to create ROC curves, both in terms of subject selection and organization of the data. In addition, discussion focuses on ROC plot interpretation using quantitative and qualitative measures. Available until 8/16/2012 • $195 APHL–CLSI Archived Webinar GP26-A4: Same Quality System Essentials, Updated Perspective CLSI documents GP26 and HS01, which focus on a model to assist with implementation and maintenance of an effective quality management system (QMS), were merged and updated in 2011 and tailored specifically to laboratories. This presentation will review these changes, including: a brief history of various editions over the last decade; a description of the major parts of the document; an explanation of the revised QMS model; major additions and changes to the Quality System Essential (QSE) requirements; and transitions needed if a laboratory already has a QSE-based QMS. 5/3/2012 • $195 APHL–CLSI Webinar plus six-month Web archive access P E C R A V (588-603-12) P E C R A V (588-608-12) Understanding Detection Capability for Quantitative IVD Assays Detection capability is a basic performance characteristic of clinical laboratory methods but can be confusing because of different types of estimates, protocols and terminology in use. This teleconference will focus on recent guidelines from CLSI document EP17 for establishment, verification and practical use of the three fundamental detection capability estimates: Limit of Blank, Detection and Quantitation (LoB, LoD and LoQ, respectively). 6/7/2012 • $195 APHL–CLSI Webinar plus six-month Web archive access How to Construct and Interpret an Error Grid for Diagnostic Assays Error grids are well-known for glucose assays, but otherwise are little used. This guideline explains the usefulness of error grids. Guidance is provided about how to establish the zones in an error grid based on the clinical implications of errors. Guidance is also provided on how to graph data from a method comparison in the error grid and estimate the proportions in each zone with confidence intervals. Examples are provided for three different assays. 5/17/2012 • $195 APHL–CLSI Webinar plus six-month Web archive access P E C R A V (588-610-12) P E C R A V (588-609-12) www.LaboratoryTraining.org Association of Public Health Laboratories 172012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=18http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=18SAfETY AND PREPAREDNESS Creating and Maintaining Safety in the Clinical Laboratory Safety and regulatory compliance are priorities for every clinical laboratory. In today’s world, it is becoming increasingly difficult to handle safety priorities on top of staff management, budget management and day-today laboratory operations. The speaker will discuss the important elements of an overall laboratory safety program and will provide advice and strategies to easily integrate these elements into the overall laboratory management program. 3/15/2012 • $195 APHL–CLSI Webinar plus six-month Web archive access Ten Years After Amerithrax: Is BT Training Still Necessary? Co-sponsors: APHL and American Society for Microbiology While 10 years has elapsed since the American anthrax attacks in the wake of the horror of 9/11/01, microbiologists remain sentinels for the recognition of emerging infectious diseases, including potential agents of bioterrorism. This presentation explores the need for continued training for sentinel microbiology laboratories in the recognition of natural and intentional infectious disease threats. Emphasis is placed on the role of the clinical microbiologist. Available until 3/20/12 Archived Webinar • $105 P E C R A V (588-605-12) Tools for Building a Safer Laboratory The risk of exposure to infectious agents continues to pose a threat in laboratories. There are new tools available such as biosafety competencies to protect laboratorians from exposures. This presentation will describe current policies and practices to reduce the risk of infection. Available until 8/7/2012 • $105 Archived Webinar P C (588-903-11) QUALITY CONTROL Uncertainty in Measurements: Estimation and Practical Use Uncertainty in measurement is internationally established in all fields of analytical chemistry, physics and other disciplines. Although measurement uncertainty is widely understood as a concept of measurement performance, reality requires a definition and consensus for the estimation and expression. We will explain the concept in metrological terms and its estimation in the laboratory, with particular emphasis on its use in laboratory medicine and practical implications in medicine. 4/5/2012 • $195 APHL–CLSI Webinar plus six-month Web archive access P C R A V (588-903-12) Select Agent Regulatory Update The CDC Select Agent Program regulates the possession, use and transfer of biological agents and toxins that could pose a severe threat to public health. The program helps ensure compliance with select agent regulations by providing guidance to registered entities and conducting evaluations and inspections. This presentation will discuss recent proposed changes of the CDC Select Agent and Import Permit Regulations. 12/4/2012 • $105 Webinar plus six-month Web archive access P C V (588-931-12) P E C R A V (588-606-12) Association of Public Health Laboratories www.LaboratoryTraining.org 182012-02-29T05:02:07+01:00http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=19http://grcdirect.ipaperus.com/APHL/APHLTrainingCatalogSpring2012/?Page=19AST The Basics: Using CLSI Antimicrobial Susceptibility Testing Standards This webinar will focus on navigating through the newest CLSI antimicrobial susceptibility testing standards M02-A11, M07-A9 and M100-S22. Strategies for optimally using these documents and incorporating recommendations into routine laboratory protocols will be discussed. Basic Level Available until 7/19/2012 • $195 Archived Webinar YEARLY TRAINING Managing Unusual Hazardous Laboratory Waste, Including the LRN-C Lab Many common laboratory wastes can be managed efficiently and at a much lower cost by bulking them together in a 55-gallon drum, treating on-site and recycling. This program will discuss some specific examples of managing waste streams associated with the Public Health (PH) Laboratory, as well as the Laboratory Response Network-Chemical (LRN-C) lab. Commonly cited laboratory hazardous waste violations will also be discussed. Available until 8/13/2012 • $105 Webinar plus six-month Web archive access P C V (588-600-12) P E CLIA 2012 CLIA Update: Mission Possible— Competency Assessments Your mission, if you choose to accept it, is to review and understand the elements required to assess the competency of laboratory personnel who perform moderate and/or high complexity laboratory testing as defined by the Clinical Laboratory Improvement Amendments (CLIA). Ideas and tips to accomplish this mission will be shared. 3/27/2012 • $105 APHL and State Hygienic Laboratory at the University of Iowa Webinar plus six-month Web archive access R (588-904-12) Bloodborne Pathogens: What, Me Worry? Need annual bloodborne pathogen training? This program begins with a brief explanation of the reasons behind the OSHA regulations (including case studies); a review of the responsibilities of both the employer and employee; proper versus improper practices; the various engineering and work practice controls, personal protective clothing and equipment, medical surveillance, Hepatitis B vaccination, signs and labels, used to ensure the safety of anyone potentially exposed to bloodborne pathogens. 9/11/2012 • $105 Webinar plus six-month Web archive access P C (588-910-12) P C R V (588-927-12) Whew! My head is so full of new knowledge I think I’ll take a nap! Association of Public Health Laboratories www.LaboratoryTraining.org 192012-02-29T05:02:07+01:00